ISHITSUKA, Hideo: search on Z-Library

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1

The design and synthesis of a new tumor-selective fluoropyrimidine carbamate, Capecitabine

Nobuo Shimma, Isao Umeda, Motohiro Arasaki, Chikako Murasaki, Kazunao Masubuchi, Yasunori Kohchi, Masanori Miwa, Masako Ura, Noriaki Sawada, Hitoshi Tahara, Isamu Kuruma, Ikuo Horii, Hideo Ishitsuka

Journal:

Bioorganic & Medicinal Chemistry

Year:

2000

Language:

english

File:

PDF, 382 KB

english, 2000

2

A Physiologically Based Pharmacokinetic Analysis of Capecitabine, a Triple Prodrug of 5-FU, in Humans: The Mechanism for Tumor-Selective Accumulation of 5-FU

Yuko Tsukamoto, Yukio Kato, Masako Ura, Ikuo Horii, Hideo Ishitsuka, Hiroyuki Kusuhara, Yuichi Sugiyama

Journal:

Pharmaceutical Research

Year:

2001

Language:

english

File:

PDF, 372 KB

english, 2001

3

Soil Nitrogen Fertility and Soybean Growth Responses to No-tillage and Manure Compost Application on Paddy-upland Rotation Fields

Nira, Rikiya, Hamaguchi, Hideo, Ishitsuka, Akiko, Sekiguchi, Tetsuo

Journal:

Communications in Soil Science and Plant Analysis

Year:

2020

File:

PDF, 962 KB

2020

4

Circulating platelet-derived endothelial cell growth factor increases in hepatocellular carcinoma patients

Kenji Jin-no, Masahito Tanimizu, Ichinosuke Hyodo, Yoshiyuki Nishikawa, Yasushi Hosokawa, Hisashi Endo, Toshihiko Doi, Koichi Mandai, Hideo Ishitsuka

Journal:

Year:

1998

Language:

english

File:

PDF, 463 KB

english, 1998

5

Murine interleukin-12 prevents the development of cancer cachexia in a murine model

Kazushige Mori, Kaori Fujimoto-Ouchi, Tohru Ishikawa, Fumiko Sekiguchi, Hideo Ishitsuka, Yutaka Tanaka

Journal:

International Journal of Cancer

Year:

1996

Language:

english

File:

PDF, 744 KB

english, 1996

6

Induction of thymidine phosphorylase expression and enhancement of efficacy of capecitabine or 5′-deoxy-5-fluorouridine by cyclophosphamide in mammary tumor models

Mika Endo, Noriko Shinbori, Yu Fukase, Noriaki Sawada, Tohru Ishikawa, Hideo Ishitsuka, Yutaka Tanaka

Journal:

International Journal of Cancer

Year:

1999

Language:

english

File:

PDF, 239 KB

english, 1999

7

Investigation of 5-FU disposition after oral administration of capecitabine, a triple-prodrug of 5-FU, using a physiologically based pharmacokinetic model in a human cancer xenograft model: comparison of the simulated 5-FU exposures in the tumour tissue between human and xenograft model

Yuko Tsukamoto, Yukio Kato, Masako Ura, Ikuo Horii, Tohru Ishikawa, Hideo Ishitsuka, Yuichi Sugiyama

Journal:

Biopharmaceutics & Drug Disposition

Year:

2001

Language:

english

File:

PDF, 274 KB

english, 2001

8

ChemInform Abstract: Discovery and Development of Novel Anticancer Drug Capecitabine

Hideo Ishitsuka, Nobuo Shimma, Ikuo Horii

Journal:

Year:

2000

File:

PDF, 24 KB

2000

9

Augmentation of the antitumor activity of capecitabine by a tumor selective dihydropyrimidine dehydrogenase inhibitor, RO0094889

Mika Endo, Masanori Miwa, Hiroyuki Eda, Masako Ura, Hiromi Tanimura, Tohru Ishikawa, Taeko Miyazaki-Nose, Kazuo Hattori, Nobuo Shimma, Hisafumi Yamada-Okabe, Hideo Ishitsuka

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 138 KB

english, 2003

10

Methylation of multiple genes as molecular markers for diagnosis of a small, well-differentiated hepatocellular carcinoma

Toyoki Moribe, Norio Iizuka, Toshiaki Miura, Naoki Kimura, Shigeru Tamatsukuri, Hideo Ishitsuka, Yoshihiko Hamamoto, Kazuhiko Sakamoto, Takao Tamesa, Masaaki Oka

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 676 KB

english, 2009

11

Establishment and characterization of cachexia-inducing and -non-inducing clones of murine colon 26 carcinoma

Kaori Fujimoto-Ouchi, Sumie Tamura, Kazushige Mori, Yutaka Tanaka, Hideo Ishitsuka

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 758 KB

english, 1995

12

Selective inhibition of spontaneous pulmonary metastasis of lewis lung carcinoma by 5′-deoxy-5-fluorouridine

Tohru Ishikawa, Masako Ura, Taeko Yamamoto, Yutaka Tanaka, Hideo Ishitsuka

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 754 KB

english, 1995

13

Expression of platelet-derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer

Masakazu Toi, Seigo Hosnina, Tadaaki Taniguchi, Yutaka Yamamoto, Hideo Ishitsuka, Takeshi Tominaga

Journal:

International Journal of Cancer

Year:

1995

Language:

english

File:

PDF, 588 KB

english, 1995

14

Rapid and quantitative detection of CpG-methylation status using TaqMan PCR combined with methyl-binding-domain polypeptide

Naoki Kimura, Toyoki Moribe, Norio Iizuka, Toshiaki Miura, Shigeru Tamatsukuri, Hideo Ishitsuka, Yoshihiko Hamamoto, Masaaki Oka

Journal:

Clinical Biochemistry

Year:

2009

Language:

english

File:

PDF, 1.20 MB

english, 2009

15

Synthetic studies of mycalolide B, an actin-depolymerizing marine macrolide: construction of the tris-oxazole macrolactone using ring-closing metathesis

Masaki Kita, Hidekazu Watanabe, Tomoya Ishitsuka, Yuzo Mogi, Hideo Kigoshi

Journal:

Tetrahedron Letters

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

16

Design and synthesis of the tumor-activated prodrug of dihydropyrimidine dehydrogenase (DPD) inhibitor, RO0094889 for combination therapy with capecitabine

Kazuo Hattori, Yasunori Kohchi, Nobuhiro Oikawa, Hitomi Suda, Masako Ura, Tohru Ishikawa, Masanori Miwa, Mika Endoh, Hiroyuki Eda, Hiromi Tanimura, Akira Kawashima, Ikuo Horii, Hideo Ishitsuka, Nobuo

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2003

Language:

english

File:

PDF, 260 KB

english, 2003

17

Restoration by recombinant interferon alpha A/D of host defense systems against tumor in immunosuppressed mice

Junko Nishimura, Kahori Mitsui, Yutaka Tanaka, Ryuko Yamamoto, Yasuji Suhara, Hideo Ishitsuka

Journal:

Clinical and Experimental Metastasis

Year:

1986

Language:

english

File:

PDF, 573 KB

english, 1986

18

Thymosin α1restores NK-cell activity and prevents tumor progression in mice immunosuppressed by cytostatics or X-rays

Yukio Umeda, Atsuko Sakamoto, Junko Nakamura, Hideo Ishitsuka, Yasuo Yagi

Journal:

Cancer Immunology, Immunotherapy

Year:

1983

Language:

english

File:

PDF, 601 KB

english, 1983

19

Protective activity of thymosin against opportunistic infections in animal models

Hideo Ishitsuka, Yukio Umeda, Junko Nakamura, Yasuo Yagi

Journal:

Cancer Immunology, Immunotherapy

Year:

1983

Language:

english

File:

PDF, 575 KB

english, 1983

20

Potentiation of the chemotherapeutic action of 5′-deoxy-5-fluorouridine in combination with guanosine and related compounds

Masaaki Iigo, Masanori Miwa, Hideo Ishitsuka, Kazuo Nitta

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1987

Language:

english

File:

PDF, 402 KB

english, 1987

21

5′-Deoxy-5-fluorouridine improves cachexia by a mechanism independent of its antiproliferative action in colon 26 adenocarcinoma-bearing mice

Hiroyuki Eda, Yutaka Tanaka, Hideo Ishitsuka

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1991

Language:

english

File:

PDF, 595 KB

english, 1991

22

Cytokines induce thymidine phosphorylase expression in tumor cells and make them more susceptible to 5′-deoxy-5-fluorouridine

Hiroyuki Eda, Kaori Fujimoto, Shin-ichi Watanabe, Masako Ura, Ayako Hino, Yutaka Tanaka, Kenji Wada, Hideo Ishitsuka

Journal:

Cancer Chemotherapy and Pharmacology

Year:

1993

Language:

english

File:

PDF, 724 KB

english, 1993

23

Antitumor and antimetastatic activities of human recombinant interferon alpha A/D

Junko Nishimura, Kahori Mitsui, Tohru Ishikawa, Yutaka Tanaka, Ryuko Yamamoto, Yasuji Suhara, Hideo Ishitsuka

Journal:

Clinical and Experimental Metastasis

Year:

1985

Language:

english

File:

PDF, 560 KB

english, 1985

24

Grain-Size Dependence of Thermal-Shock Resistance of Yttria-Doped Tetragonal Zirconia Polycrystals

Masayuki Ishitsuka, Tsugio Sato, Tadashi Endo, Masahiko Shimada, Hideo Ohno, Naoki Igawa, Takanori Nagasaki

Journal:

Journal of the American Ceramic Society

Year:

1990

Language:

english

File:

PDF, 261 KB

english, 1990

25

Comparative Antitumor Activity of 5-Fluorouracil and 5′-Deoxy-5-fluorouridine in Combination with Radiation Therapy in Mice Bearing Colon 26 Adcnocarcinoma

Tohru Ishikawa, Yutaka Tanaka, Hideo Ishitsuka, Tomohiko Ohkawa

Journal:

Year:

1989

File:

PDF, 485 KB

1989

26

Comparative Antitumor Activity and Intestinal Toxicity of 5′-Deoxy-5-fluorouridine and Its Prodrug Trimethoxybenzoyl-5′-deoxy-5-fluorocytidine

Yasuyuki Ninomiya, Masanori Miwa, Hiroyuki Eda, Hiroshi Sahara, Kaori Fujimoto, Masako Ishida, Isao Umeda, Kazuteru Yokose, Hideo Ishitsuka

Journal:

Year:

1990

File:

PDF, 550 KB

1990

27

Cytokines Induce Uridine Phosphorylase in Mouse Colon 26 Carcinoma Cells and Make the Cells More Susceptible to 5′-Deoxy-5-fluorouridine

Hiroyuki Eda, Kaori Fujimoto, Shin-ichi Watanabe, Tohru Ishikawa, Toshio Ohiwa, Kenji Tatsuno, Yutaka Tanaka, Hideo Ishitsuka

Journal:

Year:

1993

File:

PDF, 441 KB

1993

28

An SV40-induced initiation factor for protein synthesis concerned with the regulation of permissiveness

Nakajima, Katsuhisa, Ishitsuka, Hideo, Oda, Kin-ichiro

Journal:

Year:

1974

File:

PDF, 533 KB

1974

29

Capecitabine: Preclinical Pharmacology Studies

Hideo Ishitsuka

Journal:

Investigational New Drugs

Year:

2000

Language:

english

File:

PDF, 152 KB

english, 2000

30

A design consideration of deflection-modulated EBS amplifier diodes

Hideo Makishima, Osamu Mitomi, Fuminori Ishitsuka

Journal:

Electronics and Communications in Japan (Part I: Communications))

Year:

1982

Language:

english

File:

PDF, 589 KB

english, 1982

31

Hemolytic activity of a cyclic peptide Ro09-0198 isolated from Streptoverticillium

Se-Young Choung, Tetsuyuki Kobayashi, Jun-ichiro Inoue, Kenji Takemoto, Hideo Ishitsuka, Keizo Inoue

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1988

Language:

english

File:

PDF, 628 KB

english, 1988

32

Interaction of a cyclic peptide, Ro09-0198, with phosphatidylethanolamine in liposomal membranes

Se-Young Choung, Tetsuyuki Kobayashi, Kenji Takemoto, Hideo Ishitsuka, Keizo Inoue

Journal:

Biochimica et Biophysica Acta (BBA) - Biomembranes

Year:

1988

Language:

english

File:

PDF, 598 KB

english, 1988

33

Release of ribosome bound transfer RNA by enzymatic digestion of messenger RNA

Hideo Ishitsuka, Akira Kaji

Journal:

Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis

Year:

1972

Language:

english

File:

PDF, 867 KB

english, 1972

34

Prevention of ribosomal donor site from occupation by aminoacyl tRNA during polypeptide synthesis

Hideo Ishitsuka, Akira Kaji

Journal:

Year:

1972

Language:

english

File:

PDF, 303 KB

english, 1972

35

Methylated cyclin D2 gene circulating in the blood as a prognosis predictor of hepatocellular carcinoma

Masahito Tsutsui, Norio Iizuka, Toyoki Moribe, Toshiaki Miura, Naoki Kimura, Shigeru Tamatsukuri, Hideo Ishitsuka, Yusuke Fujita, Yoshihiko Hamamoto, Ryouichi Tsunedomi, Michihisa Iida, Yoshihiro Toku

Journal:

Clinica Chimica Acta

Year:

2010

Language:

english

File:

PDF, 337 KB

english, 2010

36

Efficient detection of hepatocellular carcinoma by a hybrid blood test of epigenetic and classical protein markers

Norio Iizuka, Masaaki Oka, Isao Sakaida, Toyoki Moribe, Toshiaki Miura, Naoki Kimura, Shigeru Tamatsukuri, Hideo Ishitsuka, Koichi Uchida, Shuji Terai, Satoyoshi Yamashita, Kiwamu Okita, Koichiro Saka

Journal:

Clinica Chimica Acta

Year:

2011

Language:

english

File:

PDF, 639 KB

english, 2011

37

Self-organizing-map-based molecular signature representing the development of hepatocellular carcinoma

Norio Iizuka, Masaaki Oka, Hisafumi Yamada-Okabe, Naohide Mori, Takao Tamesa, Toshimasa Okada, Norikazu Takemoto, Kazuhiko Sakamoto, Kenji Hamada, Hideo Ishitsuka, Takanobu Miyamoto, Shunji Uchimura,

Journal:

Year:

2005

Language:

english

File:

PDF, 1.27 MB

english, 2005

38

Comparative studies on the antirhinovirus activity and the mode of action of the rhinovirus capsid binding agents, chalcone amides

Yasuyuki Ninomiya, Nobuo Shimma, Hideo Ishitsuka

Journal:

Antiviral Research

Year:

1990

Language:

english

File:

PDF, 638 KB

english, 1990

39

Comparative studies on the mechanism of action of lincomycin, streptomycin, and erythromycin

Kazuei Igarashi, Hideo Ishitsuka, Akira Kaji

Journal:

Biochemical and Biophysical Research Communications

Year:

1969

Language:

english

File:

PDF, 290 KB

english, 1969

40

Synthesis and biological activities of the tris-oxazole macrolactone analogs of mycalolides

Masaki Kita, Hirotaka Oka, Akihiro Usui, Tomoya Ishitsuka, Yuzo Mogi, Hidekazu Watanabe, Hideo Kigoshi

Journal:

Year:

2012

Language:

english

File:

PDF, 609 KB

english, 2012

41

Tumor Selective Delivery of 5-Fluorouracil by Capecitabine, a New Oral Fluoropyrimidine Carbamate, in Human Cancer Xenografts

Tohru Ishikawa, Masahiro Utoh, Noriaki Sawada, Miwa Nishida, Yu Fukase, Fumiko Sekiguchi, Hideo Ishitsuka

Journal:

Biochemical Pharmacology

Year:

1998

Language:

english

File:

PDF, 421 KB

english, 1998

42

Recurrence after endoscopic polypectomy of sigmoid colon carcinoma with submucosal invasion

Koji Koinuma, Kazutomo Togashi, Fumio Konishi, Tsuneo Ishitsuka, Masaki Okada, Hideo Nagai, Nobuyuki Kanai

Journal:

Gastrointestinal Endoscopy

Year:

2001

Language:

english

File:

PDF, 260 KB

english, 2001

43

Release of tRNA from Ribosomes by a Factor other than G Factor

Hideo Ishitsuka and Akira Kaji

Journal:

Proceedings of the National Academy of Sciences

Year:

1970

Language:

english

File:

PDF, 724 KB

english, 1970

44

Drug Targeting Mini-Symposium of the Division for Medicinal Chemistry (DMC) of the Swiss Chemical Society (SCS), at the Department of Chemistry, University of Basel, May 29, 2008

Duncan, Ruth, Ojima, Iwao, Neri, Dario, Shimma, Nobuo, Okabe, Hisafumi, Ishitsuka, Hideo, Märki, Hans Peter

Journal:

CHIMIA International Journal for Chemistry

Year:

2008

Language:

english

File:

PDF, 3.98 MB

english, 2008

45

Total Synthesis of Mycalolides A and B through Olefin Metathesis

Kita, Masaki, Oka, Hirotaka, Usui, Akihiro, Ishitsuka, Tomoya, Mogi, Yuzo, Watanabe, Hidekazu, Tsunoda, Masaki, Kigoshi, Hideo

Journal:

Angewandte Chemie

Year:

2015

Language:

english

File:

PDF, 881 KB

english, 2015

46

ChemInform Abstract: Total Synthesis of Mycalolides A and B Through Olefin Metathesis.

Kita, Masaki, Oka, Hirotaka, Usui, Akihiro, Ishitsuka, Tomoya, Mogi, Yuzo, Watanabe, Hidekazu, Tsunoda, Masaki, Kigoshi, Hideo

Journal:

Year:

2016

File:

PDF, 13 KB

2016

47

Total Synthesis of Mycalolides A and B through Olefin Metathesis

Kita, Masaki, Oka, Hirotaka, Usui, Akihiro, Ishitsuka, Tomoya, Mogi, Yuzo, Watanabe, Hidekazu, Tsunoda, Masaki, Kigoshi, Hideo

Journal:

Angewandte Chemie International Edition

Year:

2015

Language:

english

File:

PDF, 892 KB

english, 2015

48

Medical procedures and outcomes of Japanese patients with trisomy 18 or trisomy 13: Analysis of a nationwide administrative database of hospitalized patients

Ishitsuka, Kazue, Matsui, Hiroki, Michihata, Nobuaki, Fushimi, Kiyohide, Nakamura, Tomoo, Yasunaga, Hideo

Journal:

American Journal of Medical Genetics Part A

Year:

2015

Language:

english

File:

PDF, 185 KB

english, 2015

49

A Simple and Efficient Microassay Method for Titration of Interferon

Ishitsuka, Hideo, Nomura, Yasuko, Takano, Kouichi

Journal:

Microbiology and Immunology

Year:

1977

Language:

english

File:

PDF, 914 KB

english, 1977

50

A NOVEL TYPE OF GLYCERIDES BEARING A METHACRYLIC ACID MOIETY FROM THE BROWN ALGA, SARGASSUM FULVELLUM

Kusumi, Takenori, Ishitsuka, Midori, Iwashita, Takashi, Naoki, Hideo, Konno, Toshinori, Kakisawa, Hiroshi

Journal:

Chemistry Letters

Year:

1981

Language:

english

File:

PDF, 6.35 MB

english, 1981

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